This workshop will provide an overview of a wide range of mental health and substance use disorders in pregnancy and postpartum (with specific focus on trauma, anxiety, PTSD and substance use including opioids and marijuana) that will impact a mother’s functionality, self-perception, emotional investment and bonding with her child(ren). Such impact psychological and biological of these conditions to maternal, fetal and infant health will be discussed, and how practitioners can evaluate risk and support recovery of the mother and well-being of the dyad. Special attention is paid to the harm of substances (including opioids) and untreated mental illness on the developing fetus and newborn (including Neonatal Abstinence Syndrome), and consequences to parenting. What are parenting attitudes and behaviors that differentiate depressed, traumatized, anxious or substance abusing parents from those who are not affected? Strategies how to encourage health seeking behaviors, and maintain emotional stability and functionality as a parent despite ongoing trauma reminders and environmental or interpersonal stressors are discussed. We will use case vignettes to illustrate illness progress, recovery, healing and treatment strategies.